(S)-(+)-2-Amino-4-phosphonobutyric acid / 1mg
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Product Description
(S)-(+)-2-Amino-4-phosphonobutyric acid is an enantiomer of the amino acid analog AP4. It is commonly used in biochemical research as a selective agonist for metabotropic glutamate receptors, specifically group III receptors.
Application:
(S)-(+)-2-Amino-4-phosphonobutyric acid is utilized in neuroscience research to study the function and modulation of metabotropic glutamate receptors, particularly group III receptors. It is also investigated for its potential therapeutic applications in neurological disorders and as a tool in drug discovery.
Articles:
- Trans-ACPD and l-APB presynaptically inhibit excitatory glutamatergic transmission in the basolateral amygdala (BLA)
Publication Date: Available online 5 March 2003
Donald G. Rainnie, Patricia Shinnick-Gallagher
https://doi.org/10.1016/0304-3940(92)90864-4
- The “ON”-bipolar agonist, L-2-amino-4-phosphonobutyrate, blocks light-evoked cone contraction in xenopus eye cups
Publication Date: January 1992
Joseph C. Besharse
https://doi.org/10.1007/BF00966867
- Response linearity and kinetics of the cat retina: The bipolar cell component of the dark-adapted electroretinogram
Publication Date: 02 June 2009
J. G. Robson and L. J. Frishman