Mertansine DM1 / 10 mg
Safety Information
Hazard Statements
Precautionary Statements
Pictograms
Properties
| Signal Word | Danger |
Product Description
Mertansine DM1 is a potent anticancer drug designed to target cancer cells specifically, minimizing harm to healthy tissues. It works by inhibiting the growth of tumors through a unique mechanism that exploits the differences between normal and cancerous cells. This targeted approach aims to enhance treatment efficacy while reducing side effects commonly associated with traditional chemotherapy. Mertansine DM1 represents a significant advancement in oncology, offering hope for patients battling various types of cancers.
Application
Mertansine DM1 is applied intravenously during a medical procedure. It is typically administered in a clinical setting under the supervision of healthcare professionals experienced in handling such medications. The treatment regimen may vary depending on the type of cancer being treated and the patient's overall health condition.
Articles:
- A Phase I Dose Escalation Study with Anti-CD44v6 Bivatuzumab Mertansine in Patients with Incurable Squamous Cell Carcinoma of the Head and Neck or Esophagus
Publication Date: OCTOBER 24 2006
Bernard M. Tijink; Jan Buter; Remco de Bree; Giuseppe Giaccone; Margreet S. Lang; Alexander Staab; C. René Leemans; Guus A.M.S. van Dongen
https://doi.org/10.1158/1078-0432.CCR-06-0910
- Cantuzumab Mertansine, a Maytansinoid Immunoconjugate Directed to the CanAg Antigen: A Phase I, Pharmacokinetic, and Biologic Correlative Study
Publication Date: January 15, 2003
Anthony W. Tolcher, Leonel Ochoa, Lisa A. Hammond, Amita Patnaik, Tam Edwards, Chris Takimoto, Lon Smith, Johann de Bono, Garry Schwartz, Theresa Mays, Zdenka L. Jonak, Randall Johnson, Mark DeWitte, Helen Martino, Charlene Audette, Kate Maes, Ravi V.J. Chari, John M. Lambert and Eric K. Rowinsky
https://doi.org/10.1200/JCO.2003.05.137
- Pharmacokinetics and Biodistribution of the Antitumor Immunoconjugate, Cantuzumab Mertansine (huC242-DM1), and Its Two Components in Mice
Publication Date: March 2004
Hongsheng Xie, Charlene Audette, Mary Hoffee, John M. Lambert and Walter A. Blättler