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L-α-Phosphatidylethanolamine, dioleoyl
L-α-Phosphatidylethanolamine, dioleoyl
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L-α-Phosphatidylethanolamine, dioleoyl / 25 MG

Purity: 99.0% (10 mg phospholipid per ml CHCl3, TLC)
Synonym: DOPE; 1,2-Dioleoyl-sn-gl; PE(18:1(9Z)/18:1(9Z)); 3-sn-Phosphatidylethanolamine; Dioleoyl phosphatidylethanolamine; 1,2-dideoyl, L-β,γ-Dioleoyl-α-cephalin; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine; 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
Molecular Formula: C41H78NO8P
Molecular Weight: 744.03
SKU: MND-38558
CAS Number: 4004-05-1
MDL number: MFCD00057986
EC Number: 200-663-8
Form: liquid
Note: Prices are for comparison only. Contact Sales for current pricing.
Packing size: 25 MG  
94.50 EUR


Safety Information


Hazard Statements

H302
H315
H319
H372
H412
H361d
H336
H351
H331

Precautionary Statements

P304 + P340 + P311
P273
P308 + P313
P302 + P352
P201
P301 + P312 + P330

Pictograms


Properties

Signal WordDanger
Flash Point (C)Not available
Flash Point (F)Not available

 Product Description

18:1 (Δ9-cis) PE (DOPE) is a phospholipid molecule composed of a glycerol backbone, two fatty acid chains, and a phosphate group. It belongs to the class of phosphatidylethanolamines and contains a cis double bond at the ninth carbon atom of one of its fatty acid chains.

 

Application:

18:1 (Δ9-cis) PE (DOPE) is commonly used as a lipid component in liposome formulations for drug delivery and as a substrate in biochemical assays for membrane studies. Its unique structure and properties make it valuable in research related to cell membrane function and lipid bilayer interactions.

 

 

 

Articles:

- The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine

Publication Date: Available online 22 October 2012

Shinichi Mochizuki, Naho Kanegae, Koichi Nishina, Yumi Kamikawa, Kazunori Koiwai, Hiroyasu Masunaga and Kazuo Sakurai

https://doi.org/10.1016/j.bbamem.2012.10.017

 

- DOPC versus DOPE as a helper lipid for gene-therapies: molecular dynamics simulations with DLin-MC3-DMA

Publication Date: 9th December 2020

Inna Ermilova and Jan Swenson

https://doi.org/10.1039/D0CP05111J

 

- Double Labeling of Oligonucleotide Probes for Fluorescence In Situ Hybridization (DOPE-FISH) Improves Signal Intensity and Increases rRNA Accessibility

Publication Date: 1 February 2010

Kilian Stoecker, Christiane Dorninger, Holger Daims, Michael Wagner

https://doi.org/10.1128/AEM.02456-09